【Introduction】
Product Name: Human TNFRSF10B / TRAILR2 / CD262 Antibody (Tilogotamab, Research Use)
Catalog Number: NBR-0894
Target Name: TNFRSF10B / TRAILR2 / CD262
Trade Name: Tilogotamab
Antibody Drug Description: Tilogotamab (GEN-1029) is an agonistic hexamer formation-enhanced mixture of two antibodies that target two separate epitopes on death receptor type 5 (DR5). Tilogotamab specifically binds to and activates DR5. Tilogotamab can be used for the research of multiple myeloma (MM).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TNFRSF10B
Synonyms: CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763