Product Name: Human TNFRSF10B / TRAILR2 / CD262 Antibody (Benufutamab, Research Use)
Catalog Number: NBR-0896
Target Name: TNFRSF10B / TRAILR2 / CD262
Trade Name: Benufutamab
Antibody Drug Description: Benufutamab (GEN1029) is a death receptor 5 (DR5) -specific agonistic antibody. Benufutamab is a mixture of 2 noncompeting DR5-specific IgG1 antibodies, each with an E430G mutation in the Fc domain. Benufutamab has antitumor effects. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  TNFRSF10B
Synonyms: CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763