Product Name: Human TNFRSF10B / TRAILR2 / CD262 Antibody (Lexatumumab, Research Use)
Catalog Number: NBR-0898
Target Name: TNFRSF10B / TRAILR2 / CD262
Trade Name: Lexatumumab
Antibody Drug Description: Lexatumumab, previously called HGS-ETR2, is a complete monoclonal antibody targeting tumor necrosis factor receptor superfamily member 10B (TNFRSF10B). It was developed by Human Genome Science (HGS) through a collaboration with Cambridge Antibody Technology and has been investigated in the treatment of various cancers. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  TNFRSF10B
Synonyms: CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763