【Introduction】
Product Name: Human ERBB1 / EGFR / HER1 Antibody (Tomuzotuximab, Research Use)
Catalog Number: NBR-0899
Target Name: ERBB1 / EGFR / HER1
Trade Name: Tomuzotuximab
Antibody Drug Description: Tomuzotuximab (or CetuGEX ®; Cetuximab biobetter - Glycotope; GT-MAB 5.2-GEX) is a novel monoclonal antibody (mAb) directed against the epidermal growth factor receptor (EGFR) with optimized and fully human glycosylation. Tomuzotuximab is optimized for glycosylation in its Fc domain to promote antibody-dependent cell-mediated cytotoxicity (ADCC).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533