【Introduction】
Product Name: Human IL-33 Antibody (Tozorakimab, Research Use)
Catalog Number: NBR-0904
Target Name: IL-33
Trade Name: Tozorakimab
Antibody Drug Description: Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab can be used to research chronic obstructive pulmonary disease.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-33
Synonyms: C9orf26; DKFZp586H0523; DVS27; IL1F11; NF-HEV
Target Description: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines.
Ensembl: ENSG00000137033
Uniprot: O95760