【Introduction】
Product Name: Human TNFRSF5 / CD40 Antibody (Iscalimab, Research Use)
Catalog Number: NBR-0906
Target Name: TNFRSF5 / CD40
Trade Name: Iscalimab
Antibody Drug Description: Iscalimab (also known as CFZ533) is a monoclonal antibody against CD40, which is involved in the interaction between T- and B-cells as well as the formation of germinal centers.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD40
Synonyms: Bp50; p50; TNFRSF5
Target Description: This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Ensembl: ENSG00000101017
Uniprot: P25942