Product Name: Human TNFRSF5 / CD40 Antibody (Lucatumumab, Research Use)
Catalog Number: NBR-0907
Target Name: TNFRSF5 / CD40
Trade Name: Lucatumumab
Antibody Drug Description: Lucatumumab is a fully humanised recombinant anti-CD40 mAb of the IgG1 isotype that blocks interaction of CD40 with its ligand CD40L inhibiting CD40L-mediated proliferation of normal B cells, CLL cells and non-Hodgkin lymphoma cells. The IgG1 antibody also mediates antibody-dependent cell-mediated cytotoxicity (ADCC). Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD40
Synonyms: Bp50; p50; TNFRSF5
Target Description: This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. 
Ensembl: ENSG00000101017
Uniprot: P25942