【Introduction】
Product Name: Human TNFSF13B / BAFF / CD257 Antibody (Tabalumab, Research Use)
Catalog Number: NBR-0915
Target Name: TNFSF13B / BAFF / CD257
Trade Name: Tabalumab
Antibody Drug Description: Tabalumab (LY2127399) is a monoclonal antibody that antagonises BLyS in both membrane and soluble forms (unlike Belimumab, which is thought to target soluble BLyS only).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TNFSF13B
Synonyms: BAFF; BLYS; CD257; TALL-1; TALL1; THANK; TNFSF20
Target Description: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Ensembl: ENSG00000102524
Uniprot: Q9Y275