Product Name: Human TNFSF5 / CD40L / CD154 Antibody (Ruplizumab, Research Use)
Catalog Number: NBR-0923
Target Name: TNFSF5 / CD40L / CD154
Trade Name: Ruplizumab
Antibody Drug Description: Ruplizumab (trade name Antova) is ahumanized monoclonal antibody.ltwas intended for the treatment ofrheumatic diseases like systemiclupus erythematosus and lupusnephritis, as well as the primary skinallograft rejection. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD40L
Synonyms: GCD154; CD40L; gp39; hCD40L; HIGM1; IMD3; TNFSF5; TRAP
Target Description: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation.
Ensembl:  ENSG00000102245
Uniprot: P29965