Product Name: Human CSF1R / M-CSFR / CD115 Antibody (Axatilimab, Research Use)
Catalog Number: NBR-0947
Target Name: CSF1R / M-CSFR / CD115
Trade Name: Axatilimab
Antibody Drug Description: Axatilimab (SNDX-6352, axa) is a humanized, full-length IgG4 antibody with high affinity to CSF-1R. Axa affects the migration, proliferation, differentiation, and survival of monocytes and macrophages by binding to CSF-1R and blocking its activation by its two known ligands, CSF-1 and IL-34. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CSF1R
Synonyms: C-FMS; CSFR; CD115
Target Description: CSF1R (Colony Stimulating Factor 1 Receptor) is a Protein Coding gene. Diseases associated with CSF1R include Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1 and Brain Abnormalities, Neurodegeneration, And Dysosteosclerosis. Among its related pathways are GPCR Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity.
Ensembl:  ENSG00000182578
Uniprot:  P07333