【Introduction】
Product Name: Human TGFB1 Antibody (Metelimumab, Research Use)
Catalog Number: NBR-0963
Target Name: TGFB1
Trade Name: Metelimumab
Antibody Drug Description: Metelimumab (CAT-192) is a human IgG4 monoclonal antibody (mAb) that neutralizes transforming growth factor beta 1 (TGF-β1) which had been chosen for further development for the treatment of diffuse cutaneous systemic sclerosis, also known as scleroderma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TGFB1
Synonyms: CED; DPD1; TGFB; TGFbeta
Target Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
Ensembl: ENSG00000105329
Uniprot: TGFB1