Product Name: Human BDCA-2 Antibody (BIIB059, Research Use)
Catalog Number: NBR-0006
Target Name: BDCA-2
Trade Name: BIIB059
Antibody Drug Description: BIIB059, discovered and developed exclusively by Biogen, is a humanized IgG1 monoclonal antibody (mAb) targeting blood dendritic cell antigen 2 (BDCA2) and is being investigated for the potential treatment of systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE) Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: BDCA-2
Synonyms: CLEC4C; CD303; CLECSF11; CLECSF7; DLEC; HECL
Target Description: CLEC4C (C-Type Lectin Domain Family 4 Member C) is a Protein Coding gene. Diseases associated with CLEC4C include Cutaneous Lupus Erythematosus and Cardiomyopathy, Dilated, 1C, With Or Without Left Ventricular Noncompaction. Among its related pathways are Innate Immune System and CLEC7A (Dectin-1) signaling. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC6A.
Ensembl: ENSG00000198178
Uniprot: Q8WTT0