【Introduction】
Product Name: Human CD27L / CD70 Antibody (Vorsetuzumab, Research Use)
Catalog Number: NBR-0020
Target Name: CD27L / CD70
Trade Name: Vorsetuzumab
Antibody Drug Description: Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer.[1] It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F (MMAF), a cytotoxic agent.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD27L / CD70
Synonyms: CD27L; CD27LG; TNFSF7
Target Description: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Ensembl: ENSG00000125726
Uniprot: P32970