【Introduction】
Product Name: Human CTLA-4 Antibody (Ipilimumab, Research Use)
Catalog Number: NBR-0025
Target Name: CTLA-4
Trade Name: Ipilimumab
Antibody Drug Description: Ipilimumab, sold under the brand name Yervoy, is a monoclonal antibody medication that works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CTLA-4
Synonyms: CTLA4; CTLA-4; CD152; GSE
Target Description: nhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Ensembl: ENSG00000163599
Uniprot: P16410