【Introduction】
Product Name: Human ALX Antibody (Tilvestamab, Research Use)
Catalog Number: NBR-0002
Target Name: AXL
Trade Name: Tilvestamab
Antibody Drug Description: Tilvestamab (BGB149) is a first-in-class, fully humanized, therapeutic anti-AXL function-blocking monoclonal antibody, discovered and developed by BerGenBio. A Phase Ia study in healthy volunteers has been completed.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: AXL
Synonyms: ARK; JTK11; Tyro7; UFO
Target Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation.
Ensembl: ENSG00000167601
Uniprot: P30530