【Introduction】
Product Name: Human CXCR4 Antibody (Ulocuplumab, Research Use)
Catalog Number: NBR-0027
Target Name: CXCR4
Trade Name: Ulocuplumab
Antibody Drug Description: Ulocuplumab (BMS-936564) binds to CXCR4 at low nanomolar concentrations ,This antibody prevents the binding of CXCL12 and inhibits calcium flux mediated cell motility and migration.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CXCR4
Synonyms: LESTR; Fusin; HM89; D2S201E; NPYY3R; HSY3RR; NPY3R; CD184; NPYR
Target Description: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation.
Ensembl: ENSG00000121966
Uniprot: 162643