【Introduction】
Product Name: Human DEC-205 Antibody (MEN1309, Research Use)
Catalog Number: NBR-0028
Target Name: DEC-205
Trade Name: MEN1309
Antibody Drug Description: MEN1309/OBT076, is an ADC comprising a fully human antibody targeting CD205, coupled to the DM4 toxin. MEN1309/OBT076 is in development for a number of CD205-driven tumors. MEN1309/OBT076 is now under early clinical investigation for patients with solid tumors and lymphoma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DEC-205
Synonyms: LY75; CLEC13B; CD205
Target Description: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
Ensembl: ENSG00000054219
Uniprot: O60449