【Introduction】
Product Name: Human DR5 / TRAILR2 Antibody (Conatumumab, Research Use)
Catalog Number: NBR-0032
Target Name: DR5 / TRAILR2
Trade Name: Conatumumab
Antibody Drug Description: Conatumumab (originally AMG-655) is a monoclonal antibody developed for the treatment of cancer. It is a fully human monoclonal agonist antibody directed against the extracellular domain of human TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) receptor 2 (TR-2, death receptor 5) with potential antineoplastic activity.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DR5
Synonyms: TRAILR2; KILLER; DR5; TRICK2A; TRICKB; CD262
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763