【Introduction】
Product Name: Human DR5 / TRAILR2 Antibody (Tigatuzumab, Research Use)
Catalog Number: NBR-0033
Target Name: DR5 / TRAILR2
Trade Name: Tigatuzumab
Antibody Drug Description: Tigatuzumab (CS-1008) is a monoclonal antibody for the treatment of cancer. As of October 2009, a clinical trial for the treatment of pancreatic cancer, Phase II trials for colorectal cancer, non-small cell lung cancer, and ovarian cancer have been completed.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DR5 / TRAILR2
Synonyms: TRAILR2; KILLER; DR5; TRICK2A; TRICKB; CD262
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763