Product Name: Human FGFR2 Antibody (Aprutumab, Research Use)
Catalog Number: NBR-0039
Target Name: FGFR2
Trade Name: Aprutumab
Antibody Drug Description: Aprutumab ixadotin is the first antibody-drug conjugate (ADC) to target FGFR2 and the first to use a novel auristatin-based payload. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: FGFR2
Synonyms: K-SAM; CD332; CEK3; TK14; TK25; ECT1; KGFR; BEK; CFD1
Target Description: FGFR2 (Fibroblast Growth Factor Receptor 2) is a Protein Coding gene. Diseases associated with FGFR2 include Pfeiffer Syndrome and Crouzon Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is FGFR1.
Ensembl: ENSG00000066468
Uniprot: P21802