【Introduction】
Product Name: Human HER2 Antibody (Zanidatamab, Research Use)
Catalog Number: NBR-0044
Target Name: HER2
Trade Name: Zanidatamab
Antibody Drug Description: zanidatamab is an engineered immunoglobulin G1 (IgG1) bi-specific monoclonal antibody that targets two different non-overlapping epitopes of the human tumor-associated antigen (TAA) epidermal growth factor receptor 2 (HER2), ECD2 and ECD4, with potential immunomodulating and antineoplastic activities.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: HER2
Synonyms: ERBB2; HER2; HER-2; CD340; NGL
Target Description: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
Ensembl: ENSG00000141736
Uniprot: P04626