
【Introduction】
Product Name: Human HER2 Antibody (Trastuzumab, Research Use)
Catalog Number: NBR-0045
Target Name: HER2
Trade Name: Trastuzumab
Antibody Drug Description: Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: HER2
Synonyms: ERBB2; HER2; HER-2; CD340; NGL
Target Description: ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2) is a Protein Coding gene. Diseases associated with ERBB2 include Visceral Neuropathy, Familial, 2, Autosomal Recessive and Glioma Susceptibility 1. Among its related pathways are Resistance of ERBB2 KD mutants to afatinib and Signaling by ERBB2 KD Mutants. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase activity. An important paralog of this gene is EGFR.
Ensembl: ENSG00000141736
Uniprot: P04626