
【Introduction】
Product Name: Human IL-18 Antibody (GSK 1070806, Research Use)
Catalog Number: NBR-0049
Target Name: IL-18
Trade Name: GSK 1070806
Antibody Drug Description: GSK1070806, an anti-IL18 monoclonal antibody, neutralizes activated (mature) IL18 released from damaged cells following inflammasome activation.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-18
Synonyms: IL1F4; IL-18; IGIF; IL-1g
Target Description: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators .
Ensembl: ENSG00000150782
Uniprot: Q14116