
【Introduction】
Product Name: Human IL-6R Antibody (Sarilumab, Research Use)
Catalog Number: NBR-0054
Target Name: IL-6R
Trade Name: Sarilumab
Antibody Drug Description: Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-6R
Synonyms: Gp80; IL-1Ra; CD126; IL-6R; IL6RA
Target Description: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal 1. Signal activation necessitate an association with IL6ST.
Ensembl: ENSG00000160712
Uniprot: P08887