【Introduction】
Product Name: Human KIR3DL2 Antibody (Lacutamab, Research Use)
Catalog Number: NBR-0057
Target Name: KIR3DL2
Trade Name: Lacutamab
Antibody Drug Description: Lacutamab (IPH4102) is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody, which is currently in clinical trials for treatment of cutaneous T-cell lymphoma (CTCL), an orphan disease.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: KIR3DL2
Synonyms: CD158K; Nkat4a; Nkat4b; NKAT-4; Nkat4
Target Description: KIR3DL2 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 2) is a Protein Coding gene. Diseases associated with KIR3DL2 include Spondylitis and Mycosis Fungoides. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is KIR3DL1.
Ensembl: ENSG00000240403
Uniprot: P43630