【Introduction】
Product Name: Human PD-1 Antibody (Spartalizumab, Research Use)
Catalog Number: NBR-0065
Target Name: PD-1
Trade Name: Spartalizumab
Antibody Drug Description: Spartalizumab is a monoclonal antibody and checkpoint inhibitor that is being investigated for melanoma.This drug is being developed by Novartis. As of 2018, spartalizumab is undergoing Phase III trials.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PD-1
Synonyms: PDCD1; CD279; HSLE1; PD-1
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116