【Introduction】
Product Name: Human PD-1 Antibody (Camrelizumab, Research Use)
Catalog Number: NBR-0066
Target Name: PD-1
Trade Name: Camrelizumab
Antibody Drug Description: Camrelizumab (SHR-1210) is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma.This drug is being developed by Jiangsu HengRui Medicine Co., Ltd. As of 2019, camrelizumab is undergoing Phase II/III trials.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PD-1
Synonyms: PDCD1; CD279; HSLE1; PD-1
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116