
【Introduction】
Product Name: Human Siglec-8 Antibody (Lirentelimab, Research Use)
Catalog Number: NBR-0083
Target Name: Siglec-8
Trade Name: Lirentelimab
Antibody Drug Description: Lirentelimab (sold under the brand name AK002) is a humanized nonfucosylated monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). In a randomized clinical trial, lirentelimab was found to improve eosinophil counts and symptoms in individuals with eosinophilic gastritis and duodenitis.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Siglec-8
Synonyms: SAF2; SIGLEC-8; SIGLEC8L
Target Description:
Ensembl: ENSG00000105366
Uniprot: Q9NYZ4