Product Name: Human TIGIT Antibody (Tiragolumab, Research Use)
Catalog Number: NBR-0085
Target Name: TIGIT
Trade Name: Tiragolumab
Antibody Drug Description: Tiragolumab is a fully human IgG1/kappa anti-TIGIT monoclonal antibody with an intact Fc region that blocks the binding of TIGIT to its receptor PVR. Investigators hypothesized that anti-TIGIT antibodies, such as tiragolumab, can restore antitumor response and potentially strengthen the activity of anti–PD-L1/PD-1 antibodies. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TIGIT
Synonyms: VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl: ENSG00000181847
Uniprot: Q495A1