Product Name: Human 4-1BB Antibody (Utomilumab, Research Use)
Catalog Number: NBR-0090
Target Name: 4-1BB
Trade Name: Utomilumab
Antibody Drug Description: Utomilumab (PF-05082566) targets CD137 receptor to stimulate a more intense immune system attack on cancers. It is a fully human IgG2 monoclonal antibody. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: 4-1BB
Synonyms: TNFRSF9; CD137; 4-1BB; ILA
Target Description: TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Immunodeficiency 16. Among its related pathways are Akt Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and cytokine binding. An important paralog of this gene is TNFRSF21.
Ensembl:  ENSG00000049249
Uniprot:  Q07011