Product Name: Human 4-1BB Antibody (Urelumab, Research Use)
Catalog Number: NBR-0091
Target Name: 4-1BB
Trade Name: Urelumab
Antibody Drug Description: Urelumab is a fully human IgG4 monoclonal antibody developed by Bristol-Myers Squibb for the treatment of cancer and solid tumors. The first phase I trial began in 2006 and final results were published in 2015. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: 4-1BB
Synonyms: TNFRSF9; CD137; 4-1BB; ILA
Target Description: TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Immunodeficiency 16. Among its related pathways are Akt Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and cytokine binding. An important paralog of this gene is TNFRSF21.
Ensembl:  ENSG00000049249
Uniprot:  Q07011