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Product Name Human ACVR2B Antibody (Bimagrumab, Research Use)
Catalog Number NBR-0095
Alias/Synonyms ActR-IIB
Appearance Transparent Liquid
Molecule Weight 150kDa
CAS N/A
Solubility Water, PBS, TBS Buffer,etc.
Storage Temp. -80℃
Shelf Life see COA
Additional info 1 CHO Expressed
Additional info 2 Ab. Isotype - IgG
Catalog Numbe Size Price Inventory Level  
NBR-0095-100UG 100ug $95 Inquire
NBR-0095-1MG 1mg $650 Inquire
NBR-0095-5MG 5mg $1395 Inquire



【Introduction】
Product Name: Human ACVR2B Antibody (Bimagrumab, Research Use)
Catalog Number: NBR-0095
Target Name: ACVR2B
Trade Name: Bimagrumab
Antibody Drug Description: Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration.

【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

 
【Gene Information】
Gene Name: ACVR2B
Synonyms: ActR-IIB
Target Description: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c).
Ensembl:  ENSG00000114739
Uniprot: Q13705
 
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