
【Introduction】
Product Name: Human Angiopoietin-2 Antibody (Nesvacumab, Research Use)
Catalog Number: NBR-0101
Target Name: Angiopoietin-2
Trade Name: Nesvacumab
Antibody Drug Description: Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2. As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Angiopoietin-2
Synonyms: Ang2
Target Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.
Ensembl: ENSG00000091879
Uniprot: O15123