Product Name: Human Angiopoietin-like3 Antibody (Evinacumab, Research Use)
Catalog Number: NBR-0102
Target Name: Angiopoietin-like3
Trade Name: Evinacumab
Antibody Drug Description: Evinacumab, sold under the brand name Evkeeza, is a monoclonal antibody medication for the treatment of homozygous familial hypercholesterolemia (HoFH).Serious hypersensitivity (allergic) reactions have occurred in the Evkeeza clinical trials. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: Angiopoietin-like3
Synonyms: ANGPTL3; ANGPT5
Target Description: ANGPTL3 (Angiopoietin Like 3) is a Protein Coding gene. Diseases associated with ANGPTL3 include Hypobetalipoproteinemia, Familial, 2 and Hypobetalipoproteinemia, Familial, 1. Among its related pathways are Plasma lipoprotein assembly, remodeling, and clearance and NR1H2 and NR1H3-mediated signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and enzyme inhibitor activity. An important paralog of this gene is ANGPT1.
Ensembl: ENSG00000132855
Uniprot: Q9Y5C1