
【Introduction】
Product Name: Human APCS Antibody (Dezamizumab, Research Use)
Catalog Number: NBR-0103
Target Name: APCS
Trade Name: Dezamizumab
Antibody Drug Description: Dezamizumab (as known as GSK2398852) is a fully humanized recombinant monoclonal IgG1 anti-serum amyloid P component (SAP) antibody, with potential anti-amyloid activity. It was developed by GlaxoSmithKline (GSK) for the treatment of AL amyloidosis (immunoglobulin light chain amyloidosis).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: APCS
Synonyms: PTX2; SAP
Target Description: APCS (Amyloid P Component, Serum) is a Protein Coding gene. Diseases associated with APCS include Candidiasis and Apolipoprotein A-Iv Associated Amyloidosis. Among its related pathways are Metabolism of proteins and RNA Polymerase I Promoter Opening. Gene Ontology (GO) annotations related to this gene include calcium ion binding and unfolded protein binding. An important paralog of this gene is CRP.
Ensembl: ENSG00000132703
Uniprot: P02743