
【Introduction】
Product Name: Human APRIL Antibody (BION-1301, Research Use)
Catalog Number: NBR-0104
Target Name: APRIL
Trade Name: BION-1301
Antibody Drug Description: BION-1301 is a proprietary monoclonal antibody therapeutic targeting APRIL, which is being evaluating for the treatment of IgA nephropathy.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: APRIL
Synonyms: TNFSF13; TALL-2; TRDL-1; CD256
Target Description: TNFSF13 (TNF Superfamily Member 13) is a Protein Coding gene. Diseases associated with TNFSF13 include Autoimmune Disease and Common Variable Immunodeficiency. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and tumor necrosis factor receptor binding. An important paralog of this gene is TNFSF13B.
Ensembl: ENSG00000161955
Uniprot: O75888