
【Introduction】
Product Name: Human B7-H3 Antibody (Enoblituzumab, Research Use)
Catalog Number: NBR-0105
Target Name: B7-H3
Trade Name: Enoblituzumab
Antibody Drug Description: Enoblituzumab is a monoclonal antibody designed for the treatment of cancer.[1] Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human B7-H3, a member of the B7 family of immune regulators.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: B7-H3
Synonyms: CD276; B7H3; B7RP-2; 4Ig-B7-H3
Target Description: CD276 (CD276 Molecule) is a Protein Coding gene. Diseases associated with CD276 include Immunodeficiency 16 and Neuroblastoma. Among its related pathways are NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is BTN1A1.
Ensembl: ENSG00000103855
Uniprot: Q5ZPR3