【Introduction】
Product Name: Human BAFF Antibody (Belimumab, Research Use)
Catalog Number: NBR-0108
Target Name: BAFF
Trade Name: Belimumab
Antibody Drug Description: Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). It is approved in the United States, Canada, and the European Union to treat systemic lupus erythematosus (SLE).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: BAFF
Synonyms: TNFSF13B; TALL-1; TALL1; BAFF; BLYS; B-Cell-Activating Factor; TNFSF20; THANK; CD257
Target Description: TNFSF13B (TNF Superfamily Member 13b) is a Protein Coding gene. Diseases associated with TNFSF13B include Sjogren Syndrome and Autoimmune Disease. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and tumor necrosis factor receptor binding. An important paralog of this gene is TNFSF13.
Ensembl: ENSG00000102524
Uniprot: Q9Y275