
【Introduction】
Product Name: Human Beta-Klotho Antibody (RG7992, Research Use)
Catalog Number: NBR-0110
Target Name: Beta-Klotho
Trade Name: RG7992
Antibody Drug Description: RG7992 (BFKB8488A) targets fibroblast growth factor receptor 1 (FGFR1) and coreceptor β klotho (KLB).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Beta-Klotho
Synonyms: KLB; BetaKlotho; B-Klotho; BKL
Target Description: KLB (Klotho Beta) is a Protein Coding gene. Diseases associated with KLB include Functional Diarrhea and Epilepsy, Idiopathic Generalized 4. Among its related pathways are Insulin receptor signalling cascade and Downstream signaling of activated FGFR2. Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL.
Ensembl: ENSG00000134962
Uniprot: Q86Z14