
【Introduction】
Product Name: Human BST2 Antibody (XmAb 5592, Research Use)
Catalog Number: NBR-0112
Target Name: BST2
Trade Name: XmAb 5592
Antibody Drug Description: XmAb5592, a humanized anti-HM1. 24 mAb with Fc-domain engineered to significantly enhance FcγR binding and associated immune effector functions. The clinical development of XmAb5592, both as a monotherapy and in combination with lenalidomide, to improve patient outcome of multiple myeloma (MM).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: BST2
Synonyms: BST2; HM1.24; CD317
Target Description: BST2 (Bone Marrow Stromal Cell Antigen 2) is a Protein Coding gene. Diseases associated with BST2 include Stomatitis and Colorado Tick Fever. Among its related pathways are SARS-CoV-1-host interactions and Innate Immune System. Gene Ontology (GO) annotations related to this gene include RNA binding and obsolete signal transducer activity.
Ensembl: ENSG00000130303
Uniprot: Q10589