Product Name: Human CAIX Antibody (Girentuximab, Research Use)
Catalog Number: NBR-0116
Target Name: CAIX
Trade Name: Girentuximab
Antibody Drug Description: Girentuximab (trade name Rencarex) is a chimeric IgG1 monoclonal antibody to carbonic anhydrase IX (CAIX). CAIX is expressed on the surface of most renal cancer cells and is hypothesized to be on the surface of other tumor cells. It is investigational agent in clinical trials for renal cell carcinoma. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CAIX
Synonyms: CA9
Target Description: CA9 (Carbonic Anhydrase 9) is a Protein Coding gene. Diseases associated with CA9 include Oncocytoma and Gum Cancer. Among its related pathways are Cellular responses to stimuli and Regulation of activated PAK-2p34 by proteasome mediated degradation. Gene Ontology (GO) annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA14.
Ensembl: ENSG00000107159
Uniprot: Q16790