
【Introduction】
Product Name: Human CCR2 Antibody (Plozalizumab, Research Use)
Catalog Number: NBR-0119
Target Name: CCR2
Trade Name: Plozalizumab
Antibody Drug Description: Plozalizumab (INN; hu1D9) is a humanized monoclonal antibody designed for the treatment of diabetic nephropathy and arteriovenous graft patency.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CCR2
Synonyms: CC-CKR-2; MCP-1-R; CMKBR2; CD192; CKR2
Target Description: CCR2 (C-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CCR2 include Human Immunodeficiency Virus Type 1 and Acquired Immunodeficiency Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR5.
Ensembl: ENSG00000121807
Uniprot: P41597