Product Name: Human CD117 Antibody (LOP628, Research Use)
Catalog Number: NBR-0122
Target Name: CD117
Trade Name: LOP628
Antibody Drug Description: LOP628 is an antibody-drug conjugate (ADC) consisting of an anti-cKit humanized IgG1/κ antibody conjugated to a maytansine payload via a non-cleavable linker. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD117
Synonyms: KIT; SCFR; C-Kit; PBT
Target Description: KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with KIT include Piebald Trait and Gastrointestinal Stromal Tumor. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Regorafenib-resistant KIT mutants. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CSF1R.
Ensembl: ENSG00000157404
Uniprot: P10721