Product Name: Human BCMA Antibody (Belantamab, Research Use)
Catalog Number: NBR-0129
Target Name: BCMA
Trade Name: Belantamab
Antibody Drug Description: Belantamab mafodotin is a humanized IgG1κ monoclonal antibody against the B-cell maturation antigen (BCMA) conjugated with a cytotoxic agent, maleimidocaproyl monomethyl auristatin F (mcMMAF). The antibody-drug conjugate binds to BCMA on myeloma cell surfaces causing cell cycle arrest and inducing antibody-dependent cellular cytotoxicity.Belantamab mafodotin is a medication for the treatment of relapsed and refractory multiple myeloma. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: BCMA
Synonyms: BCM; TNFRSF13A; CD269; BCMA
Target Description: TNFRSF17 (TNF Receptor Superfamily Member 17) is a Protein Coding gene. Diseases associated with TNFRSF17 include Lymphoma and Macroglobulinemia. Among its related pathways are TGF-Beta Pathway and MIF Mediated Glucocorticoid Regulation. Gene Ontology (GO) annotations related to this gene include signaling receptor activity. An important paralog of this gene is TNFRSF13C.
Ensembl: ENSG00000048462
Uniprot: Q02223