
【Introduction】
Product Name: Human CD46 Antibody (FOR46, Research Use)
Catalog Number: NBR-0135
Target Name: CD46
Trade Name: FOR46
Antibody Drug Description: FOR46 is a novel antibody-drug conjugate (ADC) against CD46, for the treatment of metastatic castration-resistant prostate cancer and late-stage multiple myeloma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD46
Synonyms: TLX; TRA2.10; MIC10; MCP
Target Description: CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and D-Minus Hemolytic Uremic Syndrome. Among its related pathways are Complement cascade and Immune response Lectin induced complement pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and enzyme inhibitor activity. An important paralog of this gene is CR1.
Ensembl: ENSG00000117335
Uniprot: P15529