Product Name: Human CLDN6 Antibody (IMAB027, Research Use)
Catalog Number: NBR-0150
Target Name: CLDN6
Trade Name: IMAB027
Antibody Drug Description: IMAB027 is a monoclonal antibody that binds to CLDN6. Preclinically IMAB027 was shown to inhibit tumor growth and to kill cancer cells by antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. This trial is a first-in-human dose escalation and dose finding Phase 1 trial of IMAB027 in patients with recurrent advanced ovarian cancer to assess the safety and tolerability, the pharmacokinetics, the antitumoral activity and the immunogenicity of IMAB027. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CLDN6
Synonyms: Skullin
Target Description: CLDN6 (Claudin 6) is a Protein Coding gene. Diseases associated with CLDN6 include Hepatitis C Virus and Hepatitis C. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling and Cell junction organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN9.
Ensembl:  ENSG00000184697
Uniprot:  ENSG00000184697