Product Name: Human CLEC12A Antibody (Tepoditamab, Research Use)
Catalog Number: NBR-0151
Target Name: CLEC12A
Trade Name: Tepoditamab
Antibody Drug Description: Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds CLEC12A on myeloid cells and CD3ε on cytotoxic T cells. It is being developed by Merus as a novel therapy for acute myeloid leukemia (AML) . Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CLEC12A
Synonyms: DCAL-2; CLL-1; MICL; CD371
Target Description: CLEC12A (C-Type Lectin Domain Family 12 Member A) is a Protein Coding gene. Diseases associated with CLEC12A include Myeloid Leukemia and Mixed Phenotype Acute Leukemia, B/Myeloid. Among its related pathways are Innate Immune System and IL-1 Family Signaling Pathways. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC1A.
Ensembl: ENSG00000172322
Uniprot: Q5QGZ9