
【Introduction】
Product Name: Human DKK1 Antibody (BHQ-880, Research Use)
Catalog Number: NBR-0161
Target Name: DKK1
Trade Name: BHQ-880
Antibody Drug Description: BHQ880 (Novartis) is a human neutralizing IgG1 anti-DKK1 monoclonal antibody that is being investigated for the prevention of SREs relating to MM and as an agent with potential anti-myeloma activity, with favourable preclinical results demonstrated in vitro.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DKK1
Synonyms: SK
Target Description: DKK1 (Dickkopf WNT Signaling Pathway Inhibitor 1) is a Protein Coding gene. Diseases associated with DKK1 include Chiari Malformation Type I and Osteoporosis, Juvenile. Among its related pathways are ncRNAs involved in Wnt signaling in hepatocellular carcinoma and Alzheimer's disease and miRNA effects. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and low-density lipoprotein particle receptor binding.
Ensembl: ENSG00000107984
Uniprot: O94907