Product Name: Human DLL4 Antibody (Demcizumab, Research Use)
Catalog Number: NBR-0162
Target Name: DLL4
Trade Name: Demcizumab
Antibody Drug Description: Demcizumab is a humanized monoclonal antibody which is used to treat patients with pancreatic cancer or non-small cell lung cancer. Demcizumab has completed phase 1 trials and is currently undergoing phase 2 trials. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: DLL4
Synonyms: Hdelta2; Delta; AOS6
Target Description: DLL4 (Delta Like Canonical Notch Ligand 4) is a Protein Coding gene. Diseases associated with DLL4 include Adams-Oliver Syndrome 6 and Adams-Oliver Syndrome. Among its related pathways are NOTCH2 Activation and Transmission of Signal to the Nucleus and Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants. Gene Ontology (GO) annotations related to this gene include calcium ion binding and Notch binding.
Ensembl: ENSG00000128917
Uniprot: Q9NR61