
【Introduction】
Product Name: Human FAP Antibody (Sibrotuzumab, Research Use)
Catalog Number: NBR-0171
Target Name: FAP
Trade Name: Sibrotuzumab
Antibody Drug Description: Sibrotuzumab is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP. In 2003 it failed a phase II clinical trial for metastatic colorectal cancer.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: FAP
Synonyms: DPPIV
Target Description: FAP (Fibroblast Activation Protein Alpha) is a Protein Coding gene. Diseases associated with FAP include Breast Ductal Carcinoma and Melanoma. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and serine-type endopeptidase activity. An important paralog of this gene is DPP4.
Ensembl: ENSG00000078098
Uniprot: Q12884